United States securities and exchange commission logo January 4, 2023 Fred Powell Chief Financial Officer LAVA Therapeutics N.V. 520 Walnut St, Suite 1150 Philadelphia, PA 19106 Re: LAVA Therapeutics N.V. Form 20-F for the Fiscal Year Ended December 31, 2021 Filed March 24, 2022 File No. 001-40241 Dear Fred Powell: We have completed our review of your filings. We remind you that the company and its management are responsible for the accuracy and adequacy of their disclosures, notwithstanding any review, comments, action or absence of action by the staff. Sincerely, Division of Corporation Finance Office of Life Sciences